Iressa (Gefitinib)

Description

Iressa® is a targeted therapy that targets and binds to the epidermal growth factor receptors (EGFR) on the surface of the cell. It is Iressa sold under the brand name Gefitinib. It belongs to a class of medicines called kinase inhibitors. It blocks a protein called ‘epidermal growth factor receptor’ (EGFR). The growth and spread of the cancer cells are involved in Protein. Many cancer cells, as well as normal cells, are found on the surface of EGFR which receives the sign from other cells and passes it on to the cell by Giving rise to a chemical reaction that changes another macromolecule. Once the signal has been Choke up it will lead to hampering the growth and multiplication of the cells.

The best advice is directed by a physician only. and it is good to take not less or more than 250mg in 24hours. No harm to take the tablets with or without Cuisine. Stay away from the bacteriostatic not less than 120 min before or 60 min after intake of IRESSA 250MG. It is not indicated in children and adolescents under 18 years. Consult your doctor before any other medicine with the Iressa. Try to avoid the combination pills. Do not intake the medicine with alcohol. it will lead to serious problems. Need to get in touch with the Advisor if you are pregnant or on the way to being pregnant for more than 2 months. Avoid driving alone or using tools or machines If you have intake the medicine as you can feel weakness o laziness. There may be or maybe not the side effects which is listed below

diarrhea, vomiting, nausea, loss of appetite, weakness, red or sore mouth, and dry mouth.

USES OF IRESSA 250MG

Treat adults with the non-small cell lung cancer

HOW IRESSA 250MG WORKS

IRESSA 250MG acts by inhibiting ‘epidermal growth factor receptor’ (EGFR) signal transduction pathways. EGFR is found on the surface of many cancer as well as normal cells which receives a signal from other cells and transmits it into the cell by causing a chemical reaction that modifies other proteins. By blocking these signals, it inhibits the growth and multiplication of the cells.

DIRECTIONS FOR USE

The recommended dose is 250 mg per day or as directed by a physician. You can take it with or without food.

SIDE EFFECTS OF IRESSA 250MG

SERIOUS

Allergic reaction, if symptoms include a swollen face, lips, tongue, or throat, difficulty to swallow, hives, nettle rash, and difficulty breathing

Serious breathlessness or sudden worsening breathlessness with a cough or fever

Severe skin reactions affecting large areas of your body which may include redness, pain, ulcers, blisters, and shedding of the skin

Eye problems such as pain, redness, watery eyes, light sensitivity, changes in vision, or in growing eyelashes

COMMON

Diarrhea, vomiting, and nausea

Skin reactions including acne-like rash, which is sometimes itchy with dry and/or cracked skin

Loss of appetite

Weakness, red or sore mouth

Dry mouth

Dry, red, or itchy eyes

Red and sore eyelids

Nail problems

Hair loss

Fever

Bleeding (such as nosebleed or blood in your urine)

Protein in the urine (shown in a urine test)

RARE

Inflammation of blood vessels in the skin

Burning sensations during urination and urgency to urinate with blood in the urine

HOW TO MANAGE SIDE EFFECTS

Skin Itching:

Avoid baths in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.

Nausea and vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals, and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take a rest in a quiet and dark room. Drink tea or coffee.

Diarrhea:

Drink a lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.

WARNING & PRECAUTIONS

PREGNANCY

IRESSA 250MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

IRESSA 250MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machinery while taking this medicine, it may make you feel dizzy.

ALCOHOL

Consumption of alcohol is not recommended during treatment with this medicine.

LIVER

IRESSA 250MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take it if you are allergic to the medicine.

LUNGS

IRESSA 250MG should be taken with caution in patients with another severe lung disease. Consult your doctor for advice.

INTERACTIONS

Talk to your doctor if you are taking:

Phenytoin or carbamazepine (for epilepsy)

Rifampicin (for tuberculosis)

Itraconazole (for fungal infections)

Barbiturates (a medicine used for sleeping problems)

Herbal remedies containing St John’s wort (Hypericum perforatum, used for depression and anxiety)

Proton-pump inhibitors, H2-antagonists, and antacids

SYNOPSIS

Drug: GefitinibPharmacological Category: Epidermal growth factor receptor’ (EGFR)Therapeutic Indication: Non-small cell lung cancer dosage Forms: Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT IRESSA 250MG

How do I take IRESSA 250MG?

Take this medicine with or without food as directed by your doctor, usually once daily.